GENERAL MEDICINE FINAL PRACTICAL LONG CASE

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HALL TICKET NUMBER: 1701006078

I've been given this case to solve in an attempt to understand the topic of "Patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan.

CASE DISCUSSION:

A 50 years old gentleman, farmer by occupation, resident of Yadadri Bhuvanagiri district came to the hospital with the following cheif complaints. 

CHEIF COMPLAINTS:

  • Distension of abdomen since 7 days
  • Pain in the abdomen since 4 days and
  • Pedal edema since 3 days
HISTORY OF PRESENT ILLNESS:

Patient was apparently asymptomatic 6 months back then he developed jaundice and he was treated for jaundice by a private medical practitioner. After that he was normal till last week.
He developed distension of abdomen 7 days back, which is insidious in onset, gradually progressive, aggravated in last 4 days and progressed to the present size. No aggravating and releiving factors.
He complaints of abdominal pain from last 3 days which is insidious in onset, gradually progressive, in the epigastrium and right hypochondrial regions without any aggravating and releiving factors. 
He also complains of swelling in both feet of Grade II since 3 days which is insidious in onset, gradually progressive, pitting type without any aggravating and releiving factors.


NO history of hemetemesis, melena, vomitings, nausea
NO history of bulky stools, black tarry and clay colored stools
NO history of fever with chills and rigor
NO history of anorexia, facial puffiness, generalised edema
NO history of evening rise of temperature, cough, night sweats
NO history of orthopnea, palpitations 
NO history of loss of weight


PAST HISTORY:

NO history of similar complaints in the past.
Not a known case of Diabetes, Hypertension, Tuberculosis, Asthma, epilepsy, hypothyroidism/hyperthyroidism, COPD, CAD and blood transfusions. 

FAMILY HISTORY:

None of the patient's parents, siblings or first degree relatives have or had similar complaints or any significant comorbidities.

PERSONAL HISTORY:

Appetite: reduced
Diet: mixed
Bladder habits: frequency of urine is reduced since 2 days
Bowel habits: constipation since last 4 days
Sleep: Adequate 
Addictions:
  • Beedi smoker: for past 30 years. 4-5 beedis per day

  • Alcoholic: chronic alcoholic previously 
From last one year, occasional alcoholic -  consumes 90ml of whiskey 
  • Toddy: occasionally 

GENERAL PHYSICAL EXAMINATION:
Patient is conscious, coherent and cooperative.
Examined after taking vaild informed consent in a well enlightened room.

Built and nourishment: moderately built and moderately nourished 
Pallor: No pallor
Icterus: No icterus
Cyanosis: No cyanosis 
Clubbing: No clubbing 
Generalised lymphadenopathy: No generalised lymphadenopathy 
Pedal edema: Grade II bilateral pedal edema








VITALS:

Temperature: afebrile
Pulse rate: 90bpm, regular rhythm, normal volume
Respiratory Rate: 22 breathes per minute, abdominothoracic type
Blood Pressure: 130/90 mm of Hg in right arm in sitting position 
GRBS: 90mg/dl
SpO2: 98% at room air

TREMORS: present



SYSTEMIC EXAMINATION: 

PER ABDOMINAL EXAMINATION

INSPECTION: 9 regions

Shape of the abdomen: globular
Distension of abdomen: distended



Flanks: full
Umbilicus: 
       Shape: everted
       Position: central
       Herniations: absent
       Discharge: absent
Skin over abdomen: smooth and shiny
No pigmentations, discolorations, scars, sinuses, fistulae, engorged veins, visible pulsations, hernial orifices, 
Genitals: normal

PALPATION

No local rise of temperature 
Tenderness: present in the epigastrium region
Hepatomegaly: absent
Splenomegaly: absent
Guarding: present 
Rigidity: absent
Renal angle tenderness: absent
No rebound tenderness
No visible peristalsis 
FLUID THRILL(with extended legs): POSITIVE 



PERCUSSION:

In supine position,
  Tympanic note - heard at midline of the abdomen 
  Dull note - heard at flanks

Shifting dullness: POSITIVE 

Liver span : could not be detected

AUSCULTATION:

Bowel sounds: decreased
No bruits



CARDIOVASCULAR SYSTEM- 

Inspection- 
The chest wall is bilaterally symmetrical
No dilated veins, scars or sinuses are seen
Apical impulse or pulsations cannot be appreciated 

Palpation-
Apical impulse is felt in the fifth intercostal space, 1 cm medial to the midclavicular line
No parasternal heave felt
No thrill felt

Percussion- 
Right and left borders of the heart are percussed 

Auscultation-
S1 and S2 heard, no added thrills and murmurs are heard

RESPIRATORY SYSTEM:

Inspection: 

Shape- elliptical 

B/L symmetrical , 

Both sides moving equally with respiration .

Palpation:

Trachea - central

Expansion of chest is symmetrical. 

Vocal fremitus - normal

Percussion: resonant bilaterally 

Auscultation:

 bilateral air entry present. Normal vesicular breath sounds heard.




CENTRAL NERVOUS SYSTEM 
Higher mental functions :-

Patient is conscious ,coherent and cooperative 
Right handed individual
Memory - immediate , short term and long term memory are assessed and are normal 
Language and speech are normal

Cranial nerves :- intact 

Sensory system :
Sensation                right        left
 Touch                       felt          felt
Pressure                    felt          felt 
Pain 
-superficial                felt          felt
-deep                           felt          felt
Proprioception
-joint position             ✔            ✔
-joint movement        ✔            ✔
Temperature             felt         felt 
Vibration                    felt         felt
Stereognosis                ✔            ✔

Motor system 

                                     Right.      Left


BULK 

Upper limbs.                  N        N

Lower limbs                    N       N


TONE

 Upper limbs.                   N      N

 Lower limbs.                  N        N


POWER

 Upper limbs.                 5/5       5/5

 Lower limbs                  5/5       5/5

Gait :- Normal
Superficial and deep reflexes are elicited
No signs ssuggestive of cerebellar dysfunction




INVESTIGATIONS:

1. HEMOGRAM: 

Hemoglobin : 9.8 g/dl

TLC : 7,200

Neutrophils : 49%

Lymphocytes : 40%

Eosinophils : 1%

Basophils : 0%

PCV : 27.4%

MCV : 92.3 fl

MCH : 33 pg

MCHC : 35.8%

RDW-CV : 17.6%

RDW-SD : 57.8 fl

RBC count : 2.97 millions/mm3

Platelet count : 1.5 lakhs/mm3

Smear : Normocytic normochromic anemia



2. Serology

HbsAg : Negative

HIV : Negative

3. ESR :

15mm/1st hour



4. Prothrombin time : 16 sec



5. APTT : 32 sec


6. Serum electrolytes :

Sodium : 133 mEq/L

Potassium : 3 mEq/L

Chloride : 94 mEq/L


7. Blood Urea : 12 mg/dl



8. Serum Creatinine : 0.8 mg/dl



9. LFT :

Total Bilirubin : 2.22 mg/dl

Direct Bilirubin : 1.13 mg/dl

AST : 147 IU/L

ALT : 48 IU/L

ALP : 204 IU/L

Total proteins : 6.3 g/dl

Serum albumin : 3 g/dl

A/G ratio : 0.9





10. Ascitic fluid :

Protein : 0.6 g/dl

Albumin : 0.34 g/dl

Sugar : 95 mg/dl



LDH : 29.3 IU/L



SAAG : 2.66 g/dl


ASCITIC FLUID CYTOLOGY:

Microscopy:
Cytology smear study shows few scattered lymphocytes, reactive mesothelial cells against a granular eosinophilic proteinaceous background.
No atypical cells are seen.
Impression: negative for malignancy 




ASCITIC FLUID CULTURE AND SENSITIVITY REPORT:
ZN staining: No acid fast bacilli seen.
Few epithelial cells with no inflammatory cells seen. No organisms seen.
No growth after 48 hours of aerobic incubation




ULTRASONOGRAPHY:

Coarse echotexture and irregular surface of liver - Chronic liver disease

Gross ascites

Gallbladder sludge



ELECTROCARDIOGRAPHY:


CHEST RADIOGRAPHY:





ASCITIC FLUID TAPPING: Done twice 









Severity of liver disease:

CHILD-PUGH-TURCOTTE SCORING SYSTEM:

Parameter                                       points asigned
                                                     1                     2                      3
Ascites                                    absent            slight             moderate
Bilirubin(mg/dl)                      <2                   2-3                    >3
Albumin(g/dl)                         >3.5              2.8-3.5                 <2.8    
Prothrombin time                  <4                   4-6                     >6
Encephalopathy                    None           Grade 1-2        grade 3-4



Interpretation:
Total score:  5-6   well compensated disease
                       7-9    significant functional compromise
                       10-15   decompensated disease

In this patient,
  
Ascites - moderate(3)
Bilirubin- 2.22mg/dl (2)
Albumin - 3g/dl (2)
Prothrombin time- 16 seconds  (3)
Encephalopathy- none(1)
Total score: 11

Therfore this patient's liver condition is in Decompensated state.


PROVISIONAL DIAGNOSIS:

This is a case of Decompensated Chronic liver disease with ascites, probably secondary to chronic alcoholism.



TREATMENT:

1. Inj. PANTOPRAZOLE 40 mg IV OD

2. Inj. LASIX 40 my IV BD

3. Inj. THIAMINE 1 Amp in 100 ml IV TID

4. Tab. SPIRONOLACTONE 50 mg BB

5. Syrup. LACTULOSE 15 ml HS

6. Syrup. POTCHLOR 10ml PO TID

7. Fluid restriction less than 1L/day

8. Salt restriction less than 2g/day

























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